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Previous Volume 330:68-69 January 6, 1994 Number 1 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: The mechanisms responsible for hypertrophy of the juxtaglomerular apparatus are not understood. We present histologic evidence to suggest that transforming growth factor 3 (TGF-3), a multifunctional cytokine, may be regulated with renin and may have an important role in this hypertrophy.

A 16-month-old hypertensive child with renal failure treated with long-term peritoneal dialysis was referred for renal transplantation. The renal failure was due to renal-artery thrombosis of a solitary left kidney that occurred after percutaneous renal angioplasty. On admission, the patient had a blood pressure of 135/85 mm Hg and was receiving captopril, hydralazine, and propranolol. . . . [Full Text of this Article]

References

This article has been cited by other articles:

• KELLY, F. J., ANDERSON, S., THOMPSON, M. M., OYAMA, T. T., KENNEFICK, T. M., CORLESS, C. L., ROMAN, R. J., KURTZBERG, L., PRATT, B. M., LEDBETTER, S. R. (1999). Acute and Chronic Renal Effects of Recombinant Human TGF-{beta}2 in the Rat. J. Am. Soc. Nephrol. 10: 1264-1273 [Abstract] [Full Text]  
• Ray, P. E., Liu, X.-H., Inagami, T., Chandra, R. S. (1998). Expression of Renin in Glomerular Nonjuxtaglomerular Cells in a Child with a Hypertensive Bartter's-Like Syndrome. NEJM 339: 632-634 [Full Text]  
• Border, W. A., Noble, N. A. (1998). Interactions of Transforming Growth Factor-{beta} and Angiotensin II in Renal Fibrosis. Hypertension 31: 181-188 [Abstract] [Full Text]