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Correspondence
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Volume 330:718-720 March 10, 1994 Number 10
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Calcium Gluconate in Severe Verapamil Intoxication

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To the Editor: Intoxication with verapamil is a serious and often fatal condition, complicated by severe hypotension and cardiac-conduction abnormalities1,2,3,4. The current therapeutic approach involves intravenous atropine, catecholamines, ventilation, and the insertion of a pacemaker.

A 65-year-old woman treated with sustained-release verapamil for hypertension was admitted to our hospital in a coma (Glasgow coma score, 4). The blood pressure was 83/63 mm Hg, and the heart rate was 42 beats per minute (atrioventricular nodal rhythm with right bundle-branch block). The results of a routine drug screening were negative. Verapamil overdose was suspected, and gastric lavage was performed. The patient . . . [Full Text of this Article]

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