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Perhaps no disease is more painful than acute polyarthritis. The inability to change the posture without agonizing pain, the drenching sweats, the prostration, utter helplessness, combine to make it one of the most distressing of febrile afflictions. A special feature of the disease is the tendency of the inflammation to subside in one joint, while developing with great intensity in another.
-- Sir William Osler, The Principles, Practice of Medicine.
Osler's vivid description of acute polyarthritis a century ago1 referred to rheumatic fever, clearly the bellwether of this group of disorders in that era. Despite its high worldwide prevalence in
Approach to Diagnosis
Infectious Arthritis
Bacterial Infection
Bacterial Endocarditis
Lyme Disease
Mycobacterial and Fungal Arthritis
Viral Arthritis
Postinfectious or Reactive Arthritis
Enteric or Urogenital Infection (Reiter's Syndrome)
Rheumatic Fever
Arthritis of Inflammatory Bowel Disease
Rheumatoid Arthritis
Systemic Rheumatic Illness
Systemic Vasculitis
Systemic Lupus Erythematosus
Crystal-Induced Arthritis
Other Disorders
Prolonged or Recurrent Illness
Source Information
From the Department of Medicine, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, New Brunswick, N.J.
Address reprint requests to Dr. Pinals at the Department of Medicine, the Medical Center at Princeton, Princeton, NJ 08540.
References
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