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Volume 330:794-795 March 17, 1994 Number 11
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Prevention of Preeclampsia with Low-Dose Aspirin

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 by Vega, W. A.
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 by Sibai, B. M.
To the Editor: In the report by Sibai et al. (Oct. 21 issue)1 on the use of low-dose aspirin to prevent preeclampsia, the overall perinatal mortality was similar in the aspirin and placebo groups (aspirin: 22 deaths among a total of 1545 fetuses, or 14.2 deaths per 1000 live births; placebo: 14 deaths among 1551 fetuses, or 9.0 deaths per 1000 live births), but the difference in the number of fetal deaths after 20 weeks' gestation was almost significant by chi-square analysis (17 deaths among 1570 fetuses vs. 7 among 1565, respectively; P = 0.06). As Zuspan and Samuels point . . . [Full Text of this Article]

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