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Previous Volume 330:862-863 March 24, 1994 Number 12 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Hull and colleagues (Nov. 4 issue)¹ compared postoperative warfarin therapy with a once-daily postoperative regimen of the low-molecular-weight heparin Logiparin for the prevention of postoperative venous thrombosis in patients undergoing major orthopedic surgery. They found a small but significant reduction in thrombosis in the low-molecular-weight-heparin group at the cost of a small but significant increase in bleeding. The event rate in the low-molecular-weight-heparin group was higher than that reported in other studies that used a twice-daily postoperative dosing regimen and mandatory venography to assess thrombosis^2,3,4,5. The observed differences in the incidence of postoperative thrombosis between the . . . [Full Text of this Article]

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