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Previous Volume 330:1026 April 7, 1994 Number 14 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Edited by Luc Montagnier and Marie-Lise Gougeon. 323 pp., illustrated. New York, Marcel Dekker, 1993. $99.75. ISBN 0-8247-9127-4.

One of the penalties of working in a field too long is that more and more of what seems important happened over a decade ago. That was when patterns of AIDS transmission were discerned, human immunodeficiency virus types 1 and 2 (HIV-1 and HIV-2) were discovered, and zidovudine, arguably our most effective antiretroviral drug, was identified. Yet the puzzle of how CD4+ T lymphocytes die in patients with AIDS -- a problem of fundamental importance to the biologic features of HIV and critical to the development of novel therapeutics -- evades our grasp. Basic knowledge of T-cell homeostasis is inchoate . . . [Full Text of this Article]

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