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Previous Volume 330:1152-1154 April 21, 1994 Number 16 Next

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In 1981 Sullivan proposed that the lower incidence of coronary heart disease in premenopausal women as compared with men and postmenopausal women is due to higher levels of stored iron in the latter two groups¹. To support this hypothesis, he cited the increased risk of coronary heart disease among women in the Framingham Study who had undergone hysterectomy but not oophorectomy, the toxic effects of iron overload on the myocardium, and the low incidence of coronary heart disease among men and women in developing countries, where iron stores are likely to be low. Lacking experimental support or a biologically . . . [Full Text of this Article]

References

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• Sun, Q., Ma, J., Rifai, N., Franco, O. H., Rexrode, K. M., Hu, F. B. (2008). Excessive Body Iron Stores Are Not Associated with Risk of Coronary Heart Disease in Women. J. Nutr. 138: 2436-2441 [Abstract] [Full Text]  
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