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Correspondence
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Volume 330:1237-1238 April 28, 1994 Number 17
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Air Pollution and Mortality

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 by Dockery, D. W.
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To the Editor: Because of the possibility of residual confounding, relative risks of the order of 1.3 or less, as reported by Dockery et al. in their study of air pollution and mortality (Dec. 9 issue),1 are difficult to interpret in epidemiologic investigations. As is common in epidemiologic studies, Dockery et al. adjusted for age by stratifying subjects into five-year age groups. Because of the strong influence of age on lung cancer and cardiovascular mortality, this stratification system may not be fine enough to detect small relative risks. For example, the mortality rate from lung cancer among smokers increases roughly . . . [Full Text of this Article]

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