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Previous Volume 330:1238-1239 April 28, 1994 Number 17 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text Purchase this article Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited Related Article by Beck, R. W.

To the Editor: The report by Beck et al. (Dec. 9 issue)¹ on the effect of corticosteroids on the subsequent development of multiple sclerosis in patients with optic neuritis comes to some stupendous and puzzling conclusions about the natural course of multiple sclerosis.

First, the Optic Neuritis Treatment Trial,² the source of the authors' data, was designed primarily to test the efficacy of corticosteroids in the treatment of acute optic neuritis. In their more recent trial¹ the authors excluded all patients who had multiple sclerosis at entry, since the primary end point of this retrospective study was the development of . . . [Full Text of this Article]

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