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Previous Volume 330:1356-1360 May 12, 1994 Number 19 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Human herpesvirus-6 (HHV-6) is the causative agent of exanthem subitum¹ and febrile illnesses² in children. More recently, HHV-6 has been shown to infect the recipients of bone marrow transplants and has been implicated in interstitial pneumonitis^3,4 and bone marrow suppression⁵ after transplantation. The pathogenicity of HHV-6, however, has yet to be fully delineated in either immunocompetent or immunocompromised hosts. In some children with exanthem subitum, seizures, encephalopathy, and the detection of HHV-6 DNA in cerebrospinal fluid have provided circumstantial evidence that HHV-6 can infect the central nervous system^6,7. Nevertheless, these studies have failed to document the direct invasion of . . . [Full Text of this Article]

Case Report

Methods

Microbiologic Surveillance and Viral-Isolation Studies

DNA Isolation, Polymerase Chain Reaction, and Sequence-Specific Oligonucleotide-Probe Hybridization

Immunohistochemical Studies

Results

Discussion

Source Information

From the Departments of Medicine (W.R.D., D.M.) and Pathology (K.K.K., D.R.C.) and the Bone Marrow Transplant Program (W.R.D., D.M.), Medical College of Wisconsin, Milwaukee.

Address reprint requests to Dr. Drobyski at the Bone Marrow Transplant Program, Box 176, 8700 W. Wisconsin Ave., Milwaukee, WI 53226.

References

This article has been cited by other articles:

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