FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |   Search Term  Advanced Search

Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe

Previous Volume 330:140-141 January 13, 1994 Number 2 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text Purchase this article Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited Related Article by Warrell, R. P. PubMed Citation

To the Editor: Warrell et al. (July 15 issue)¹ do an excellent job of correlating the molecular and clinical aspects of acute promyelocytic leukemia. Less convincing, however, is their attribution of a "syndrome characterized by fever, respiratory distress, radiographic pulmonary infiltrates, pleural effusions, and weight gain" with "extensive infiltration of myeloid cells" to the administration of all-trans-retinoic acid. Before retinoic acid was used in the treatment of acute promyelocytic leukemia, fever and pulmonary manifestations of capillary leakage were described in patients with acute myeloid leukemia with or without hyperleukocytosis^2,3 and ascribed to the invasiveness of promyeloblasts or the release of . . . [Full Text of this Article]

References

This article has been cited by other articles:

• De Botton, S., Dombret, H., Sanz, M., Miguel, J. S., Caillot, D., Zittoun, R., Gardembas, M., Stamatoulas, A., Conde, E., Guerci, A., Gardin, C., Geiser, K., Makhoul, D. C., Reman, O., de la Serna, J., Lefrere, F., Chomienne, C., Chastang, C., Degos, L., Fenaux, P., Group, t. E. A. (1998). Incidence, Clinical Features, and Outcome of All Trans-Retinoic Acid Syndrome in 413 Cases of Newly Diagnosed Acute Promyelocytic Leukemia. Blood 92: 2712-2718 [Abstract] [Full Text]