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Previous Volume 330:141-143 January 13, 1994 Number 2 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Johnson et al. (Aug. 5 issue)¹ found that oral pilocarpine improved saliva production and relieved the symptoms of xerostomia after irradiation for cancer of the head and neck. They state that other drugs have no proved clinical benefit.

Carbachol, another parasympathomimetic drug, has also been used in functional bladder and gastrointestinal disorders to stimulate the bowel function. Its side effects include sweating, nausea and emesis, hypersalivation, and in large doses, bradycardia.

We recently treated 16 patients with radiation-induced xerostomia, first with oral pilocarpine solution (6 mg three times daily) for three months and then, after a four-week . . . [Full Text of this Article]

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