In 1985 the Journal published a paper from the multicenter NationalSurgical Adjuvant Breast and Bowel Project (NSABP) showing thatlumpectomy was as effective as mastectomy in the treatment ofearly breast cancer1. A follow-up paper in 1989 confirmed thefinding2. It was published in the Journal along with two otherpapers from the NSABP: one showing that adjuvant chemotherapywas effective for node-negative, estrogen-receptor-negativebreast cancer,3 and the other showing that tamoxifen was effectivefor node-negative, estrogen-receptor-positive breast cancer4.The trials (known as Protocols B-06, B-13, and B-14) were coordinatedby Dr. Bernard Fisher of the . . . [Full Text of this Article]
References
Related Letters:
The NSABP Trials
Levenback C., Bross I. D., Davis N., Heitjan D. F., Altman L. K., Angell M., Kassirer J. P.
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N Engl J Med 1994;
331:809-810, Sep 22, 1994.
Correspondence
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Levenback, C., Bross, I. D., Davis, N., Heitjan, D. F., Altman, L. K., Angell, M., Kassirer, J. P.
(1994). The NSABP Trials. NEJM
331: 809-810
[Full Text]