FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |   Search Term  Advanced Search

Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe

Previous Volume 330:292 January 27, 1994 Number 4 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text Purchase this article Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited Related Article by Spach, D. H.

To the Editor: In their excellent review of tick-borne diseases (Sept. 23 issue),¹ Spach et al. recommended tetracyclines for most adults with Rocky Mountain spotted fever and chloramphenicol for those with "prominent central nervous system manifestations of disease." The majority of patients with Rocky Mountain spotted fever have central nervous system symptoms; Spach et al. mention that 90 percent of patients have a severe headache. I can remember few patients with the disease whose neurologic symptoms would not be considered prominent.

Although chloramphenicol penetrates the blood-brain barrier better than tetracyclines, I know of no evidence that higher antibiotic concentrations in . . . [Full Text of this Article]

References

HOME  |  SUBSCRIBE  |  SEARCH  |  CURRENT ISSUE  |  PAST ISSUES  |  COLLECTIONS  |  PRIVACY  |  HELP  |  beta.nejm.org Comments and questions? Please contact us. The New England Journal of Medicine is owned, published, and copyrighted © 2008 Massachusetts Medical Society. All rights reserved.