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Correspondence
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Volume 330:574-575 February 24, 1994 Number 8
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A Predictive Model for Non-Hodgkin's Lymphoma

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 by The International Non-Hodgkin's Lymphoma Prognostic Factors Project
To the Editor: The model of Shipp et al. for predicting survival in patients with aggressive non-Hodgkin's lymphoma (Sept. 30 issue)1 may represent an improvement over staging alone, but the approximations that the authors use in simplifying their model may limit its value in comparing different groups of treated patients or in assigning risk to an individual patient. The generalizability of their results is limited by several factors.

First, the authors treat the relative risks of the five independent variables as equal, whereas the true values vary by as much as 14 percent from the mean.

Second, in the model . . . [Full Text of this Article]

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