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Previous Volume 330:577 February 24, 1994 Number 8 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Administration of oleic and erucic acids ("Lorenzo's oil"), a widely used therapy for patients with adrenoleukodystrophy or adrenomyeloneuropathy,^1,2 is associated with thrombocytopenia³. We studied 15 men with adrenomyeloneuropathy and 3 symptomatic heterozygous women. The patients followed a low-fat diet with restricted intake of C26:0 fatty acid and received a mean (±SD) of 1.28 ±0.14 g of glycerol trioleate oil (Karlshamns, Columbus, Ohio) and 0.23 ±0.02 g of glycerol trierucate oil (Croda Universal, Liverpool, United Kingdom) per kilogram of body weight per day.

Asymptomatic thrombocytopenia developed in five patients (whose platelet counts ranged between 37,000 and 84,000 . . . [Full Text of this Article]

References

This article has been cited by other articles:

• van Geel, B M, Assies, J, Haverkort, E B, Koelman, J H T M, Verbeeten, B Jr, Wanders, R J A, Barth, P G (1999). Progression of abnormalities in adrenomyeloneuropathy and neurologically asymptomatic X-linked adrenoleukodystrophy despite treatment with "Lorenzo's oil". J. Neurol. Neurosurg. Psychiatry 67: 290-299 [Abstract] [Full Text]