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Review Article
Current Concepts
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Volume 331:656-660 September 8, 1994 Number 10
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Acid-Reflux Disorders
Charles E. Pope

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In recent years, the concept of acid-reflux disorders has been broadened to include not only the effects of gastroesophageal reflux on the esophageal mucosa but also the role of acid reflux in laryngeal and pulmonary symptoms. This review discusses the effects of reflux on the esophagus, larynx, and lungs, emphasizing similarities and differences between gastrointestinal and respiratory manifestations of acid reflux.

Esophageal Reflux

Pathophysiology

For the past 20 years, it was assumed that the lower esophageal sphincter is the primary determinant of esophageal reflux. It is now recognized, however, that transient relaxation of the lower esophageal sphincter, not the resting pressure level, is . . . [Full Text of this Article]

Diagnosis

Therapy

Acid Laryngitis

Pulmonary Disease and Reflux


Source Information

From the Department of Medicine, Seattle Veterans Affairs Medical Center, and the Department of Medicine, University of Washington, Seattle.

Address reprint requests to Dr. Pope at the Division of Gastroenterology RG-24, University of Washington, Seattle, WA 98195.

References


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