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Correspondence
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Volume 331:676-678 September 8, 1994 Number 10
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Recombinant Erythropoietin in Very-Low-Birth-Weight Infants

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 by Maier, R. F.
To the Editor: The report by Maier et al. (April 28 issue)1 on the effect of epoetin beta (recombinant human erythropoietin) in very-low-birth-weight infants provides important new data on the efficacy and safety of the agent in this age group. However, the results of Maier et al. raise several questions. First, what does their success rate tell us about anemia in these infants? The anemia of prematurity reaches a nadir by 6 to 10 weeks of age,2 a period barely covered by data on the first 45 days of life. As presented, the data could indicate that the need for . . . [Full Text of this Article]

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