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Previous Volume 331:679-680 September 8, 1994 Number 10 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Papadopoulos et al. (April 28 issue)¹ report complete remission in five patients who received unmanipulated donor T cells as therapy for Epstein-Barr virus (EBV)-associated lymphoproliferation after allogeneic bone marrow transplantation. We have administered donor T cells to a patient in whom this complication developed, and we agree that this therapy produces clinical responses. However, its wider application may be limited by substantial toxicity.

A three-year-old boy with juvenile chronic myeloid leukemia presented with fevers, pulmonary nodules, and retroperitoneal lymphadenopathy eight months after the transplantation of T-cell-depleted bone marrow, with two mismatched antigens, from his brother. A biopsy . . . [Full Text of this Article]

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