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Correspondence
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Volume 331:683 September 8, 1994 Number 10
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More Poison from Agatha Christie

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To the Editor: Orah and Richard Platt's entertaining review of The Poisonous Pen of Agatha Christie (April 14 issue)1 contains a regrettable error regarding the solubility of arsenic trioxide. The statement is made that this poison, although minimally soluble in cold water, is "exquisitely suited to hot cocoa, tea, or milk, where 20 to 60 times the lethal dose (6 g) is undetectable in two teaspoons of drink." This implies that 6 g of arsenic trioxide is soluble in 10 ml of hot aqueous liquid. Actually, the solubility of the substance in boiling water is 1 in 152; thus, . . . [Full Text of this Article]

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