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Review Article
Medical Progress
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Volume 331:717-727 September 15, 1994 Number 11
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Bleeding Peptic Ulcer
Loren Laine, and Walter L. Peterson

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Peptic ulcer is the most common cause of acute hemorrhage in the upper gastrointestinal tract, accounting for about 50 percent of cases1,2,3,4,5,6,7,8,9,10,11,12,13,14. There are approximately 150,000 hospitalizations per year in the United States for evaluation and treatment of bleeding ulcers (based on 1985 estimates and excluding federal hospitals)15. Although hospitalization and surgery for uncomplicated ulcers have decreased in the United States and Europe over the past 20 to 30 years, the number of hospital admissions for hemorrhage associated with ulcers has remained relatively unchanged15,16,17. It is noteworthy that the incidence of bleeding ulcers appears to rise in . . . [Full Text of this Article]

Pathogenesis

Histologic Features

Predisposing Factors

Clinical Presentation

Clinical Prognostic Factors

Prognostic Features at Endoscopy

Initial Management

Treatment of Acute Bleeding Episodes

Medical Therapy

Endoscopic Therapy

Surgical Therapy

Angiographic Therapy

Prevention of Recurrent Bleeding

Medical Therapy

Surgical Therapy


Source Information

From the Department of Medicine, University of Southern California School of Medicine, and the Los Angeles County and University of Southern California Medical Center, Los Angeles (L.L.); and the University of Texas Southwestern Medical School and the Medical Service, Dallas Veterans Affairs Medical Center, Dallas (W.L.P.).

Address reprint requests to Dr. Peterson at Digestive Diseases (111B1), Dallas VA Medical Center, 4500 S. Lancaster Rd., Dallas, TX 75216.

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