The human and financial costs of lower-extremity amputationin patients with diabetes mellitus are well recognized1. However,the rates of major amputation in the United States remain high,2in part because present knowledge regarding the prevention andmanagement of foot disease is not widely applied in clinicalpractice. The U.S. Department of Health has set a goal for theyear 2000 of a 40 percent reduction in amputation rates amongdiabetic patients3. Methods to achieve this goal are availabletoday. For example, in the majority of diabetic patients, theinitial condition that eventually leads to amputation is a . . . [Full Text of this Article]
The Neuropathic Ulcer
The Role of Neuropathy
The Role of Mechanical Stress
Management of Neuropathic Ulcers
Prevention of Neuropathic Ulcers
Infection
Surgical Aspects
Summary
Source Information
From the Department of Medicine, Pennsylvania State University College of Medicine, Milton S. Hershey Medical Center, Hershey, Pa. (G.M.C., P.R.C., J.S.U.); and the Departments of Surgery (G.W.G.) and Medicine (A.W.K.), New England Deaconess Hospital, Harvard Medical School, Boston.
Address reprint requests to Dr. Caputo at the Division of General Internal Medicine, Milton S. Hershey Medical Center, 500 University Dr., Hershey, PA 17033.
References
Related Letters:
Foot Disease in Diabetes
Goldenheim P. D., Gohdes D., Rith-Najarian S., Capelli-Schellpfeffer M., Philipson L. H., Caputo G. M., Ulbrecht J. S., Gibbons G. W.
Extract |
Full Text
N Engl J Med 1995;
332:269-270, Jan 26, 1995.
Correspondence
This article has been cited by other articles:
Zgonis, T., Stapleton, J. J., Roukis, T. S.
(2008). A Stepwise Approach to the Surgical Management of Severe Diabetic Foot Infections. Foot & Ankle Specialist
1: 46-53
[Abstract]
Pataky, Z., Golay, A., Rieker, A., Grandjean, R., Schiesari, L., Vuagnat, H.
(2007). A First Evaluation of an Educational Program for Health Care Providers in a Long-Term Care Facility to Prevent Foot Complications. INT J LOW EXTREM WOUNDS
6: 69-75
[Abstract]
Goretti, C., Mazzurco, S., Nobili, L. A., Macchiarini, S., Tedeschi, A., Palumbo, F., Scatena, A., Rizzo, L., Piaggesi, A.
(2007). Clinical Outcomes of Wide Postsurgical Lesions in the Infected Diabetic Foot Managed With 2 Different Local Treatment Regimes Compared Using a Quasi-Experimental Study Design: A Preliminary Communication. INT J LOW EXTREM WOUNDS
6: 22-27
[Abstract]
Huizinga, M. M., Peltier, A.
(2007). Painful Diabetic Neuropathy: A Management-Centered Review. Clin. Diabetes
25: 6-15
[Abstract][Full Text]
Dini, V., Romanelli, M., Piaggesi, A., Stefani, A., Mosca, F.
(2006). Cutaneous tissue engineering and lower extremity wounds (part 2).. INT J LOW EXTREM WOUNDS
5: 27-34
[Abstract]
Clifft, J. K., Kasser, R. J., Newton, T. S., Bush, A. J.
(2005). The Effect of Monochromatic Infrared Energy on Sensation in Patients With Diabetic Peripheral Neuropathy: A double-blind, placebo-controlled study. Diabetes Care
28: 2896-2900
[Abstract][Full Text]
Legat, F. J., Krause, R., Zenahlik, P., Hoffmann, C., Scholz, S., Salmhofer, W., Tscherpel, J., Tscherpel, T., Kerl, H., Dittrich, P.
(2005). Penetration of Piperacillin and Tazobactam into Inflamed Soft Tissue of Patients with Diabetic Foot Infection. Antimicrob. Agents Chemother.
49: 4368-4371
[Abstract][Full Text]
Giurini, J. M., Lyons, T. E.
(2005). Diabetic Foot Complications: Diagnosis and Management. INT J LOW EXTREM WOUNDS
4: 171-182
[Abstract]
Lipsky, B. A., Berendt, A. R., Deery, H. G., Embil, J. M., Joseph, W. S., Karchmer, A. W., LeFrock, J. L., Lew, D. P., Mader, J. T., Norden, C., Tan, J. S.
(2005). Diagnosis and Treatment of Diabetic Foot Infections. J. Am. Podiatr. Med. Assoc.
95: 183-210
[Full Text]
Chang, H. R., Aksenov, I. V., Boulton, A. J.M., Kirsner, R. S., Vileikyte, L.
(2004). Neuropathic Diabetic Foot Ulcers. NEJM
351: 1694-1695
[Full Text]
McCall, D. T., Sauaia, A., Hamman, R. F., Reusch, J. E., Barton, P.
(2004). Are Low-Income Elderly Patients at Risk for Poor Diabetes Care?. Diabetes Care
27: 1060-1065
[Abstract][Full Text]
Zimny, S., Schatz, H., Pfohl, M.
(2004). The Role of Limited Joint Mobility in Diabetic Patients With an At-Risk Foot. Diabetes Care
27: 942-946
[Abstract][Full Text]
Smith, C. L.
(2004). Pharmacotherapy of Diabetic Foot Ulcers. Journal of Pharmacy Practice
17: 66-74
[Abstract]
Duffin, A. C., Kidd, R., Chan, A., Donaghue, K. C.
(2003). High Plantar Pressure and Callus in Diabetic Adolescents: Incidence and Treatment. J. Am. Podiatr. Med. Assoc.
93: 214-220
[Abstract][Full Text]
Dupre, J.-C., Dechamps, E., Pillu, M., Despeyroux, L.
(2003). The Fitting of Amputated and Nonamputated Diabetic Feet: A French Experience at the Villiers-Saint-Denis Hospital. J. Am. Podiatr. Med. Assoc.
93: 221-228
[Abstract][Full Text]
Legat, F. J., Maier, A., Dittrich, P., Zenahlik, P., Kern, T., Nuhsbaumer, S., Frossard, M., Salmhofer, W., Kerl, H., Muller, M.
(2003). Penetration of Fosfomycin into Inflammatory Lesions in Patients with Cellulitis or Diabetic Foot Syndrome. Antimicrob. Agents Chemother.
47: 371-374
[Abstract][Full Text]
DeNamur, C., Pupp, G.
(2002). Diabetic Limb Salvage: A Team Approach at a Teaching Institution. J. Am. Podiatr. Med. Assoc.
92: 457-462
[Abstract][Full Text]
Ledermann, H. P., Morrison, W. B., Schweitzer, M. E.
(2002). Pedal Abscesses in Patients Suspected of Having Pedal Osteomyelitis: Analysis with MR Imaging. Radiology
224: 649-655
[Abstract][Full Text]
Viswanathan, V, Snehalatha, C, Seena, R, Ramachandran, A
(2002). Early recognition of diabetic neuropathy: evaluation of a simple outpatient procedure using thermal perception. Postgrad. Med. J.
78: 541-542
[Abstract][Full Text]
Frykberg, R. G., Bailey, L. F., Matz, A., Panthel, L. A., Ruesch, G.
(2002). Offloading Properties of a Rocker Insole: A Preliminary Study. J. Am. Podiatr. Med. Assoc.
92: 48-53
[Abstract][Full Text]
Zimny, S., Reinsch, B., Schatz, H., Pfohl, M.
(2001). Effects of Felted Foam on Plantar Pressures in the Treatment of Neuropathic Diabetic Foot Ulcers. Diabetes Care
24: 2153-2154
[Full Text]
Zimny, S., Dessel, F., Ehren, M., Pfohl, M., Schatz, H.
(2001). Early Detection of Microcirculatory Impairment in Diabetic Patients With Foot at Risk. Diabetes Care
24: 1810-1814
[Abstract][Full Text]
de Lalla, F., Pellizzer, G., Strazzabosco, M., Martini, Z., Du Jardin, G., Lora, L., Fabris, P., Benedetti, P., Erle, G.
(2001). Randomized Prospective Controlled Trial of Recombinant Granulocyte Colony-Stimulating Factor as Adjunctive Therapy for Limb-Threatening Diabetic Foot Infection. Antimicrob. Agents Chemother.
45: 1094-1098
[Abstract][Full Text]
Faglia, E., Favales, F., Morabito, A.
(2001). New Ulceration, New Major Amputation, and Survival Rates in Diabetic Subjects Hospitalized for Foot Ulceration From 1990 to 1993: A 6.5-year follow-up. Diabetes Care
24: 78-83
[Abstract][Full Text]
Romeo, J. H.
(2000). Comprehensive versus Holistic Care: Case Studies of Chronic Disease. J Holist Nurs
18: 352-361
[Abstract]
SCHÖMIG, M., RITZ, E., STANDL, E., ALLENBERG, J.
(2000). The Diabetic Foot in the Dialyzed Patient. J. Am. Soc. Nephrol.
11: 1153-1159
[Full Text]
Akbari, C. M., Pomposelli, F. B. Jr, Gibbons, G. W., Campbell, D. R., Pulling, M. C., Mydlarz, D., LoGerfo, F. W.
(2000). Lower Extremity Revascularization in Diabetes: Late Observations. Arch Surg
135: 452-456
[Abstract][Full Text]
Bello, Y. M., Phillips, T. J.
(2000). Recent Advances in Wound Healing. JAMA
283: 716-718
[Full Text]
Joshi, N., Caputo, G. M., Weitekamp, M. R., Karchmer, A.W.
(1999). Infections in Patients with Diabetes Mellitus. NEJM
341: 1906-1912
[Full Text]
Pittet, D., Wyssa, B., Herter-Clavel, C., Kursteiner, K., Vaucher, J., Lew, P. D.
(1999). Outcome of Diabetic Foot Infections Treated Conservatively: A Retrospective Cohort Study With Long-term Follow-up. Arch Intern Med
159: 851-856
[Abstract][Full Text]
Erstad, B. L., McIntyre, K. E. JR
(1997). Prospective, Randomized Comparison of Ampicillin/Sulbactam and Cefoxitin for Diabetic Foot Infections. VASC ENDOVASCULAR SURG
31: 419-426
[Abstract]
Lew, D. P., Waldvogel, F. A.
(1997). Osteomyelitis. NEJM
336: 999-1007
[Full Text]
Gohdes, D., Rith-Najarian, S., Acton, K., Shields, R.
(1996). Improving Diabetes Care in the Primary Health Setting: The Indian Health Service Experience. ANN INTERN MED
124: 149-152
[Abstract][Full Text]
Goldenheim, P. D., Gohdes, D., Rith-Najarian, S., Capelli-Schellpfeffer, M., Philipson, L. H., Caputo, G. M., Ulbrecht, J. S., Gibbons, G. W.
(1995). Foot Disease in Diabetes. NEJM
332: 269-270
[Full Text]