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Previous Volume 331:870-871 September 29, 1994 Number 13 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Medullary thyroid carcinoma, a tumor of the thyroid parafollicular cells (C cells) that secrete calcitonin, constitutes about 10 percent of all thyroid cancers, being considerably less common than papillary or follicular thyroid carcinoma. It occurs as both a sporadic and a familial disease. Among families, it occurs alone or as a component of either multiple endocrine neoplasia type 2A (MEN-2A), comprising medullary thyroid carcinoma, pheochromocytoma, and hyperparathyroidism, or the rarer MEN-2B, comprising medullary thyroid carcinoma, pheochromocytoma, and mucosal neuromas. Medullary thyroid carcinoma was among the first cancers whose genetic features were exploited for prevention. This was achieved by recognizing that . . . [Full Text of this Article]

References

This article has been cited by other articles:

• Lora, M. S., Waguespack, S. G., Moley, J. F., Walvoord, E. C. (2005). Adrenal Ganglioneuromas in Children with Multiple Endocrine Neoplasia Type 2: A Report of Two Cases. J. Clin. Endocrinol. Metab. 90: 4383-4387 [Abstract] [Full Text]