Genetics is a language with rules of composition that give thetissues of the body their special traits. These rules governthe activation of particular subgroups of genes, which determinenot only the unique characteristics of a cell type but alsowhether it remains quiescent, divides, or dies. The timing ofgene activation is very important. If genes are activated inthe wrong order, a cell may miss a critical step in its development.Moreover, the expression of a gene at the wrong time in thecell's life cycle is a frequent misstep in the progression towardcancer. Understanding the . . . [Full Text of this Article]
Pitot, H. C.
(1998). The Progression of Neoplasia, Cell Replication, and Electromagnetic Fields. International Journal of Toxicology
17: 59-108
Haywood, G. A., Gullestad, L., Katsuya, T., Hutchinson, H. G., Pratt, R. E., Horiuchi, M., Fowler, M. B.
(1997). AT1 and AT2 Angiotensin Receptor Gene Expression in Human Heart Failure. Circulation
95: 1201-1206
[Abstract][Full Text]
Majzoub, J. A., Muglia, L. J.
(1996). Knockout Mice. NEJM
334: 904-906
[Full Text]
Rosenthal, N.
(1995). Recognizing DNA. NEJM
333: 925-927
[Full Text]
Stoeckle, M., Rosenthal, N., Schwartz, R. S.
(1995). The Molecular Medicine Series. NEJM
332: 1240-1241
[Full Text]
Papavassiliou, A. G.
(1995). Transcription Factors. NEJM
332: 45-47
[Full Text]