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Previous Volume 331:1207-1211 November 3, 1994 Number 18 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Idiopathic thrombocytopenic purpura (ITP), also referred to as primary immune thrombocytopenic purpura, is defined by a low platelet count, normal bone marrow, and the absence of other causes of thrombocytopenia. This review focuses on ITP and its management in adults. Typically, adult ITP is a chronic disease.

Clinical Features

Presentation

Among adults, ITP is most common in young women: 72 percent of patients over 10 years old are women, and 70 percent of these women are less than 40 years old¹. The onset is often insidious. History and physical examination are normal except for symptoms and signs of the type of bleeding . . . [Full Text of this Article]

Laboratory Evaluation

Differential Diagnosis

Course and Prognosis

Pathophysiology

Management

Initial Management

Management of Severe Bleeding

Management of ITP in Pregnancy

Splenectomy

Management of Persistent Thrombocytopenia

Source Information

From the Hematology-Oncology Section, Department of Medicine (J.N.G., M.A.E.-H., G.E.R.), and the Department of Biostatistics and Epidemiology (G.E.R.), University of Oklahoma Health Sciences Center, Oklahoma City.

Address reprint requests to Dr. George at the Hematology-Oncology Section, Department of Medicine, University of Oklahoma Health Sciences Center, P.O. Box 26901, Oklahoma City, OK 73190.

References

Related Letters:

Chronic Idiopathic Thrombocytopenic Purpura
Bibas M., Garrido J. A., George J. N., El-Harake M., Raskob G. E.
Extract | Full Text  
N Engl J Med 1995; 332:685-686, Mar 9, 1995. Correspondence

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