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Correspondence
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Volume 331:1235-1236 November 3, 1994 Number 18
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Diuretic Therapy and the Risk of Cardiac Arrest

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 by Siscovick, D. S.
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 by Mills, J. A.
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To the Editor: Siscovick et al. (June 30 issue)1 report that higher doses of thiazide diuretics were associated with an increased risk of cardiac arrest. They state that they corrected for the differences between the case and control patients, but this may have been difficult because so many factors differed between the two groups. The case patients were older, and in this group the pretreatment systolic blood pressure was higher, the pretreatment heart rate was faster, the duration of hypertension was longer, and there were more men, more smokers, and more patients with diabetes mellitus. Such a group would be . . . [Full Text of this Article]

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