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Previous Volume 331:1308-1309 November 10, 1994 Number 19 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Saper and Breder provide a comprehensive review of the neurologic basis of fever (June 30 issue).¹ Thermoregulation involves a complex interaction of autonomic, endocrine, and behavioral responses governed largely by the hypothalamus. Damage in the preoptic region, which functions as a thermostat and contains mechanisms for heat dissipation, may cause heat intolerance or thermostatic dysfunction, and no fever response will occur.^1,2 Lesions of the posterior hypothalamus or brain stem may destroy the pathways for autonomic and behavioral thermoregulation, with consequent hypothermia or poikilothermy.²

The authors do not clearly differentiate between fever and non-pyrogen-induced hyperthermia. Fever is a . . . [Full Text of this Article]

References

This article has been cited by other articles:

• Stephan, F., Ghiglione, S., Decailliot, F., Yakhou, L., Duvaldestin, P., Legrand, P. (2005). Effect of excessive environmental heat on core temperature in critically ill patients. An observational study during the 2003 European heat wave. Br J Anaesth 94: 39-45 [Abstract] [Full Text]