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Previous Volume 331:1449-1450 November 24, 1994 Number 21 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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The intravascular administration of iodinated contrast agents is part of many diagnostic and therapeutic radiologic procedures. Since these agents have no therapeutic value, it is important that they be safe. The contrast agents that have been in use for many years have a high osmolality and are ionic, and their administration has been associated with anaphylactoid events, cardiovascular instability, and nephrotoxicity. Recently, low-osmolality contrast agents, ionic and nonionic, have been introduced to reduce the incidence of side effects.

Nephrotoxicity caused by contrast agents is usually identified clinically by an increase in the serum creatinine concentration. In many studies, the condition . . . [Full Text of this Article]

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