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Previous Volume 331:1500-1507 December 1, 1994 Number 22 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Tumors of the central nervous system constitute the largest group of solid neoplasms in children and are second only to leukemia in their overall frequency during childhood. Each year, brain tumors develop in approximately 1500 to 2000 children in the United States; the number of tumors appears to have increased slightly from 1974 to 1988^1,2,3. Although the mortality rate for these neoplasms exceeds the rates for many other childhood tumors, recent therapeutic advances coupled with refinements in neuroimaging techniques, which have facilitated earlier diagnosis and improved treatment planning, have increased the percentage of affected children who survive to adulthood^2,3. . . [Full Text of this Article]

Classification of Brain Tumors in Children

Clinical Features

Diagnostic Evaluation

General Principles of Treatment

Surgical Therapy

Radiotherapy

Chemotherapy and Other Adjuvant Treatments

Treatment and Outcome of Common Brain Tumors in Children

Low-Grade Gliomas

Supratentorial Malignant (High-Grade) Gliomas

Medulloblastomas (Infratentorial Primitive Neuroectodermal Tumors)

Brain-Stem Gliomas

Ependymomas

Craniopharyngiomas

Late Sequelae of Treatment

Conclusions

Source Information

From the Department of Neurosurgery, Children's Hospital of Pittsburgh and University of Pittsburgh School of Medicine, Pittsburgh.

Address reprint requests to Dr. Pollack at the Department of Neurosurgery, Children's Hospital of Pittsburgh, 3705 Fifth Ave., Pittsburgh, PA 15213.

References

Related Letters:

Brain Tumors in Children
Brown W. D., Gilles F. H., Pollack I. F.
Extract | Full Text  
N Engl J Med 1995; 332:1238-1239, May 4, 1995. Correspondence

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