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Previous Volume 331:1517-1519 December 1, 1994 Number 22 Next

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The three disease processes responsible for most ischemic strokes are large-vessel atherothrombotic disease (accounting for about 14 percent of ischemic strokes), small-vessel atherothrombotic or lipohyalinotic disease (i.e., lacunar stroke, accounting for about 27 percent), and embolic disease (accounting for about 59 percent).^1,2 Among patients with large-vessel atherothrombotic disease leading to ischemic strokes and transient cerebral ischemic attacks, two thirds have stenosis of more than 70 percent at the bifurcation of the common carotid artery.^3,4 In these circumstances, properly selected symptomatic patients, and possibly also asymptomatic patients, benefit from expertly performed carotid endarterectomy. Among the other one third of patients with . . . [Full Text of this Article]

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