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Correspondence
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Volume 331:1529 December 1, 1994 Number 22
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Familial Occurrence of Neurocardiogenic Syncope

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To the Editor: Cooper et al. (July 21 issue)1 described neurocardiogenic syncope in a mother and daughter. The authors stated that they were "not aware of a familial clustering of this disorder." In fact, there have been several previous reports suggesting a genetic predisposition to neurocardiogenic syncope. A case-control study by Camfield and Camfield2 showed that among children with vasovagal (neurocardiogenic) syncope, a significant proportion had a parent or sibling with syncope, an association not seen in control subjects. In a study by Kleinknecht et al.3 of college students with vasovagal syncope, a significant familial association was seen. Talwar et . . . [Full Text of this Article]

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