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Previous Volume 331:1689-1692 December 22, 1994 Number 25 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Although decreases in regional cerebral blood flow are known to occur in relation to migraine headache, the pattern of the alterations in blood flow has not been precisely delineated. Olesen et al. have described a series of patients who had migraine headaches during serial cerebral blood-flow measurement by the intracarotid xenon-133 technique.¹ They observed a pattern of localized decreases in flow that appeared to spread contiguously along the cerebral cortex. These observations were confirmed in subsequent studies,^2,3 and with very few exceptions^1,4 the pattern of "spreading oligemia" or "spreading hypoperfusion"⁵ has been apparent only in patients who have migraine headaches . . . [Full Text of this Article]

Case Report

Methods

Results

Discussion

Source Information

From the Division of Brain Mapping, Neuropsychiatric Institute (R.P.W., M.I., J.C.M.), and the Departments of Neurology (R.P.W., M.I., J.C.M.), Psychology (M.I.), Pharmacology (J.C.M.), and Radiology (J.C.M.), UCLA School of Medicine, Los Angeles.

Address reprint requests to Dr. Woods at the Department of Neurology, UCLA School of Medicine, 710 Westwood Plaza, Los Angeles, CA 90024.

References

Related Letters:

Spreading Cerebral Hypoperfusion during Migraine Headache
Vijayan N., O'Brien M. D., Blau J.N., Rastegar D., Woods R. P., Iacoboni M., Mazziotta J. C., Olesen J.
Extract | Full Text  
N Engl J Med 1995; 332:1516-1518, Jun 1, 1995. Correspondence

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