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Previous Volume 331:1711-1712 December 22, 1994 Number 25 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Chronic tubulointerstitial nephritis and nephritis of unknown origin account for 15 to 30 percent of the cases of end-stage renal disease (ESRD) in the United States and Europe. A substantial but as yet undetermined proportion of these cases may be due to drug-induced nephrotoxicity. Evaluating the role of nephrotoxic drugs is a critical health care issue because of the opportunity to prevent ESRD. In 1953 Spuhler and Zollinger¹ suggested that the prolonged ingestion of analgesic drugs could cause tubulointerstitial nephritis (so-called analgesic nephropathy), and subsequently many studies confirmed their hypothesis. As a consequence, phenacetin was withdrawn from the market. The . . . [Full Text of this Article]

References

This article has been cited by other articles:

• Curhan, G. C., Knight, E. L., Rosner, B., Hankinson, S. E., Stampfer, M. J. (2004). Lifetime Nonnarcotic Analgesic Use and Decline in Renal Function in Women. Arch Intern Med 164: 1519-1524 [Abstract] [Full Text]  
• Colson, P., Ryckwaert, F., Cittanova, M.-L. (2002). ACE Inhibitor and Postoperative Renal Dysfunction * Response. Anesth. Analg. 95: 499-500 [Full Text]  
• Cittanova, M.-L., Zubicki, A., Savu, C., Montalvan, C., Nefaa, N., Zaier, K., Riou, B., Coriat, P. (2001). The Chronic Inhibition of Angiotensin-Converting Enzyme Impairs Postoperative Renal Function. Anesth. Analg. 93: 1111-1115 [Abstract] [Full Text]  
• Cittanova, M. L. (2001). Editorial II: Is peri-operative renal dysfunction of no consequence?. Br J Anaesth 86: 164-166 [Full Text]  
• Trinkhaus, J., Nathan, J., Beane, L., Meltzer, B. (1997). Acetaminophen (Tylenol): Johnson & Johnson and Consumer Safety. J Law Med Ethics 25: 49-57