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Editorial
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Volume 331:1770-1771 December 29, 1994 Number 26
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Iodine Deficiency and Fetal Brain Damage

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Iodine deficiency is by far the most common preventable cause of mental deficits in the world. The evidence for this statement has emerged from a variety of disciplines, including epidemiology, endocrinology, and neurology.1

The most severe effect of iodine deficiency is endemic cretinism, which is characterized by the combination of mental deficiency, deaf-mutism, and motor rigidity or, less commonly, by severe hypothyroidism. The two forms are often referred to as neurologic cretinism and hypothyroid cretinism, respectively. They may occur separately or together.1 Both types of cretinism are associated with iodine deficiency that is sufficiently severe to cause goiter in 30 . . . [Full Text of this Article]

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