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Correspondence
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Volume 331:1776 December 29, 1994 Number 26
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Case 30-1994: Antiendomysial Antibodies and Celiac Disease

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 by Kelly, C. P.
To the Editor: With respect to the case report regarding a 74-year-old woman with diarrhea, dehydration, and weight loss (Aug. 11 issue),1 we believe the discussants left us tantalizingly short of important clinical and laboratory information that would boost the reader's confidence in the final diagnosis. We were surprised that there was no mention of the estimation of antibodies such as antigliadin antibody or, more particularly, antiendomysial antibody in the investigation of small-bowel diarrhea, tests that in our experience have a specificity approaching 100 percent.2 Indeed, a positive test for endomysial antibodies would substantially increase the probability that a gluten-sensitive . . . [Full Text of this Article]

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