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Previous Volume 331:325-327 August 4, 1994 Number 5 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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The application of molecular biology to the treatment of patients with cancer took root in pediatric oncology with the landmark demonstration of the association of amplification of the N-myc oncogene with a poor prognosis in children with neuroblastoma¹. Today, amplification of N-myc and the amount of DNA in tumor cells are factors that can determine the intensity of therapy for neuroblastoma. Neuroblastoma belongs to a family of primitive small-round-cell tumors, which often cause diagnostic difficulties because of their homogeneous appearance on light microscopy and their frequent lack of organ specificity. Any of these tumors can be hidden in the . . . [Full Text of this Article]

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• Castex, M.-P., Rubie, H., Stevens, M. C.G., Escribano, C. C., de Gauzy, J. S., Gomez-Brouchet, A., Rey, A., Delattre, O., Oberlin, O. (2007). Extraosseous Localized Ewing Tumors: Improved Outcome With Anthracyclines--The French Society of Pediatric Oncology and International Society of Pediatric Oncology. JCO 25: 1176-1182 [Abstract] [Full Text]