To the Editor: Opelz and Wujciak and their colleagues are tobe congratulated for maintaining a multicenter registry in theCollaborative Transplant Study (March 24 issue)1. However, beforetheir recommendations for realigning the organ-delivery systemare implemented, they must first prove that the degree of HLAmismatching has an effect on the incidence and severity of theserious complication graft arteriosclerosis, which currentlylimits long-term survival of heart-transplant recipients2.
Furthermore, it is unrealistic to propose that 20 percent oforgans can be safely set aside for emergency transplantations.As has been shown, the overall trend is for transplantation. . . [Full Text of this Article]
References
This article has been cited by other articles:
Hauptman, P. J., O'Connor, K. J.
(1997). Procurement and Allocation of Solid Organs for Transplantation. NEJM
336: 422-431
[Full Text]