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Correspondence
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Volume 331:481 August 18, 1994 Number 7
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Acyclovir for Herpes Zoster

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 by Wood, M. J.
To the Editor: In their report on the treatment of acute herpes zoster (March 31 issue),1 Wood et al. state that "intravenous and oral acyclovir in immunocompetent patients are associated with significant improvements in the rate of healing and the severity of the acute pain of herpes zoster," and that "because the benefits of acyclovir therapy during the acute phase are established, it was considered unethical to include a placebo group." Although the authors report a well-executed study, we would like to put these two statements into perspective.

It is true that in each of the published controlled studies, including . . . [Full Text of this Article]

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