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Previous Volume 332:688 March 9, 1995 Number 10 Next

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Edited by Balz Frei. 588 pp. San Diego, Calif., Academic Press, 1994. $99. ISBN 0-12-266975-4.

The first 128 pages of this book contain four chapters that clearly summarize the basics of free-radical chemistry, the generation of free radicals in biologic tissues, and the nature of antioxidant defense systems in mammals. The balance of the book (16 chapters) deals with current knowledge relating antioxidants (mainly natural antioxidants) to cancer, cardiovascular disease, immunity and infection, cataracts, and neurologic disorders.

The reviews of basic studies — of cell-culture, animal, and epidemiologic studies — make a persuasive case for a connection between free radicals and diseases. However, a pattern quickly emerges in the chapters dealing with disease. Despite the . . . [Full Text of this Article]

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