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Correspondence
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Volume 332:819-821 March 23, 1995 Number 12
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Burkholderia cepacia in Cystic Fibrosis

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 by Steinbach, S.
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To the Editor: Steinbach et al. (Oct. 13 issue)1 address an important and contentious issue — the transmissibility of Burkholderia (formerly Pseudomonas) cepacia among patients with cystic fibrosis. The authors used genomic fingerprinting of B. cepacia isolates based on pulsed-field gel electrophoresis (PFGE) and concluded that the bacterium was not spread among patients cared for at the University of North Carolina Cystic Fibrosis Center. Their conclusion was based on the observation that genetic differences could be discerned among strains by PFGE (which analyzes the entire bacterial genome) but not by the widely accepted method of ribotype analysis (which detects . . . [Full Text of this Article]

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