FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |   Search Term  Advanced Search

Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe

Previous Volume 332:1025-1027 April 13, 1995 Number 15 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text Purchase this article Letters Letters Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited PubMed Citation

Truly elegant clinical science defines syndromes with precision, delineates pathogenic mechanisms, and compares treatments in prospective randomized trials. Conventional clinical science lacks precision and applies empirical remedies. According to these definitions, the clinical science focused on the antiphospholipid-antibody syndrome is conventional now, but on the verge of becoming elegant.

The diagnosis of the antiphospholipid-antibody syndrome¹ requires that a patient have recurrent clinical events (such as thromboses or fetal loss) and an antiphospholipid antibody (such as anticardiolipin antibody or lupus anticoagulant). The syndrome is "primary" if there is no accompanying autoimmune disease and "secondary" if the patient also has systemic lupus . . . [Full Text of this Article]

References

Related Letters:

Thrombosis in the Antiphospholipid-Antibody Syndrome
Violi F., Ferro D., Valesini G., Rapaport S. I., Le D. T., Slivka A., Walz E., Cole A. J., Nasr S. Z., Parke A. L., Khamashta M. A., Taub N. A., Hunt B. J., Lockshin M. D.
Extract | Full Text  
N Engl J Med 1995; 333:665-667, Sep 7, 1995. Correspondence

Prevention of Preterm Birth
McGregor J. A., French J. I., Sepkowitz S., Devitt N., Goldenberg R. L., Rouse D. J.
Extract | Full Text  
N Engl J Med 1998; 339:1858-1860, Dec 17, 1998. Correspondence

This article has been cited by other articles:

• Fernandes de Godoy, M., Braile, D. M., Torres, C. A. A., Pereira de Godoy, J. M. (2000). Prevalence of Anticardiolipin Antibodies in Peripheral Arterial Thrombosis. ANGIOLOGY 51: 473-477 [Abstract]  
• FOSCHI, F. G, MARSIGLI, L., BERNARDI, M., SALVI, F., MASCALCHI, M., GASBARRINI, G., STEFANINI, G. F (2000). Acute multifocal cerebral white matter lesions during transfer factor therapy. J. Neurol. Neurosurg. Psychiatry 68: 114-115 [Full Text]  
• McGregor, J. A., French, J. I., Sepkowitz, S., Devitt, N., Goldenberg, R. L., Rouse, D. J. (1998). Prevention of Preterm Birth. NEJM 339: 1858-1860 [Full Text]  
• Hill, J. A. (1997). Immunotherapy for Recurrent Pregnancy Loss: "Standard of Care of Buyer Beware". Reproductive Sciences 4: 267-273  
• McDonagh, J., Khamashta, M., Menon, S., Rahman, A., Isenberg, D. (1997). Grand Rounds from International Lupus Centres A young woman with SLE: diagnostic and therapeutic challenges. Lupus 6: 633-637  
• Hojnik, M., George, J., Ziporen, L., Shoenfeld, Y. (1996). Heart Valve Involvement (Libman-Sacks Endocarditis) in the Antiphospholipid Syndrome. Circulation 93: 1579-1587 [Abstract] [Full Text]  
• Gatenby, P. (1996). Neurological and obstetric manifestations of the antiphospholipid syndrome. Lupus 5: 170-172 [Abstract]  
• Violi, F., Ferro, D., Valesini, G., Rapaport, S. I., Le, D. T., Slivka, A., Walz, E., Cole, A. J., Nasr, S. Z., Parke, A. L., Khamashta, M. A., Taub, N. A., Hunt, B. J., Lockshin, M. D. (1995). Thrombosis in the Antiphospholipid-Antibody Syndrome. NEJM 333: 665-667 [Full Text]  
• (1995). Anticoagulation for Antiphospholipid Antibody Syndrome. Journal Watch Dermatology 1995: 13-13 [Full Text]  
• (1995). ANTICOAGULATION FOR ANTIPHOSPHOLIPID ANTIBODY SYNDROME. JWatch General 1995: 5-5 [Full Text]