FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |   Search Term  Advanced Search

Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe

Previous Volume 332:1302-1304 May 11, 1995 Number 19 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text Purchase this article Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited Related Article by Scognamiglio, R. PubMed Citation

To the Editor: It is unfortunate that Scognamiglio et al. (Sept. 15 issue)¹ chose to use digoxin instead of placebo to study the effects of nifedipine in asymptomatic patients with chronic, severe aortic regurgitation. Almost two decades since the short-term beneficial effects of vasodilator therapy in severe aortic regurgitation were first reported,² clinicians still await proof that vasodilator therapy reduces or delays the need for aortic-valve replacement in asymptomatic patients with severe, chronic aortic regurgitation. Although some authors^3,4 have promoted the routine use of vasodilators to delay the need for valve replacement in these patients, an informal survey we made . . . [Full Text of this Article]

References

This article has been cited by other articles:

• Evangelista, A., Tornos, P., Sambola, A., Permanyer-Miralda, G., Soler-Soler, J. (2005). Long-term vasodilator therapy in patients with severe aortic regurgitation.. NEJM 353: 1342-1349 [Abstract] [Full Text]  
• Gaasch, W. H., Schick, E. C. (2003). Symptoms and left ventricular size and function in patients with chronic aortic regurgitation. J Am Coll Cardiol 41: 1325-1328 [Full Text]