The risk of tuberculosis among health care workers was substantialin the era before antibiotics1 but declined rapidly after 1950because of the lower incidence of the disease in the populationand the advent of effective therapy. These changes resultedin the relaxation of infection-control practices in hospitals,if not outright neglect of such practices. Over the past decade,two factors have profoundly altered views about the risk oftuberculosis in health care workers. The first is the resurgenceof the disease. Between 1985 and 1991, the incidence of allforms of tuberculosis increased by 24 to 34 percent in . . . [Full Text of this Article]
Estimates of the Risk of Tuberculous Disease
Estimates of the Risk of Tuberculous Infection
Reports of Nosocomial Transmission
Theoretical Basis for Nosocomial Transmission of Tuberculosis
Evidence in Support of Recommended Control Measures
Diagnosis and Therapy
Ventilation
Ultraviolet Light
Masks
Tuberculin Screening
Bacille CalmetteGuérin Vaccination
Effect of Measures to Control Infection
Conclusions
Recommendations
Source Information
From the Departments of Medicine, Epidemiology, and Biostatistics, McGill University, Montreal (D.M.); the Tuberculosis Services, Alberta Health, Edmonton (A.F.); the Department of Preventive Medicine and Biostatistics, University of Toronto, Toronto (L.Y.); and Vancouver General Hospital and the University of British Columbia, Vancouver (M.F.) all in Canada.
Address reprint requests to Dr. Menzies at Montreal Chest Hospital, 3650 St. Urbain, Montreal, QC H2X 2P4, Canada.
References
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de Vries, G., Sebek, M. M. G. G., Lambregts-van Weezenbeek, C. S. B.
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28: 1216-1221
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Djelouagji, Z., Drancourt, M.
(2006). Inactivation of Cultured Mycobacterium tuberculosis Organisms Prior to DNA Extraction. J. Clin. Microbiol.
44: 1594-1595
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Cahn, P., Perez, H., Ben, G., Ochoa, C.
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OLENDER, S., SAITO, M., APGAR, J., GILLENWATER, K., BAUTISTA, C. T., LESCANO, A. G., MORO, P., CAVIEDES, L., HSIEH, E. J., GILMAN, R. H.
(2003). LOW PREVALENCE AND INCREASED HOUSEHOLD CLUSTERING OF MYCOBACTERIUM TUBERCULOSIS INFECTION IN HIGH ALTITUDE VILLAGES IN PERU. Am J Trop Med Hyg
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Menzies, D., Fanning, A., Yuan, L., FitzGerald, J. M.
(2003). Factors Associated with Tuberculin Conversion in Canadian Microbiology and Pathology Workers. Am. J. Respir. Crit. Care Med.
167: 599-602
[Abstract][Full Text]
Tanoue, L. T., Mark, E. J.
(2003). Case 1-2003 - A 43-Year-Old Man with Fever and Night Sweats. NEJM
348: 151-161
[Full Text]
Chedore, P., Th'ng, C., Nolan, D. H., Churchwell, G. M., Sieffert, D. E., Hale, Y. M., Jamieson, F.
(2002). Method for Inactivating and Fixing Unstained Smear Preparations of Mycobacterium tuberculosis for Improved Laboratory Safety. J. Clin. Microbiol.
40: 4077-4080
[Abstract][Full Text]
Greenaway, C., Menzies, D., Fanning, A., Grewal, R., Yuan, L., FitzGerald, J. M., The Canadian Collaborative Group in Nosocomial Tra,
(2002). Delay in Diagnosis among Hospitalized Patients with Active Tuberculosis-Predictors and Outcomes. Am. J. Respir. Crit. Care Med.
165: 927-933
[Abstract][Full Text]
Moreno, S., Blazquez, R., Novoa, A., Carpena, I., Menasalvas, A., Ramirez, C., Guerrero, C.
(2001). The Effect of BCG Vaccination on Tuberculin Reactivity and the Booster Effect Among Hospital Employees. Arch Intern Med
161: 1760-1765
[Abstract][Full Text]
Menzies, D., Fanning, A., Yuan, L., FitzGerald, J. M., the Canadian Collaborative Group in Nosocomial Tra,
(2000). Hospital Ventilation and Risk for Tuberculous Infection in Canadian Health Care Workers. ANN INTERN MED
133: 779-789
[Abstract][Full Text]
Schwartzman, K., Menzies, D.
(1999). Tuberculosis: 11. Nosocomial disease. CMAJ
161: 1271-1277
[Full Text]
Riska, P. F., Su, Y., Bardarov, S., Freundlich, L., Sarkis, G., Hatfull, G., Carrière, C., Kumar, V., Chan, J., Jacobs, W. R. Jr.
(1999). Rapid Film-Based Determination of Antibiotic Susceptibilities of Mycobacterium tuberculosis Strains by Using a Luciferase Reporter Phage and the Bronx Box. J. Clin. Microbiol.
37: 1144-1149
[Abstract][Full Text]
Newman, L. S.
(1995). Occupational Illness. NEJM
333: 1128-1134
[Full Text]