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Review Article
Drug Therapy
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Volume 332:99-110 January 12, 1995 Number 2
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Benign Prostatic Hyperplasia — Medical and Minimally Invasive Treatment Options
Joseph E. Oesterling, M.D.

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Benign prostatic hyperplasia is a nonmalignant enlargement of the prostate that is due to excessive cellular growth of both the glandular and the stromal elements of the gland. The condition is very common in men over 40 years of age of all races and cultures.1,2,3,4,5,6,7,8 For the past 50 years, transurethral resection of the prostate has been the mainstay of treatment. Approximately 400,000 such resections are performed annually in the United States, making this operation the second most common after cataract extraction in men older than 65.9 The associated expense is considerable; the total cost is approximately $5 billion per . . . [Full Text of this Article]

Evaluating Treatment Options

Medical Treatments

Androgen-Deprivation Therapy

Drugs That Inhibit 5{alpha}-Reductase Activity

{alpha}-Adrenergic–Antagonist Drugs

Summary of Medical Therapies

Minimally Invasive Treatments

Transurethral Incision of the Prostate

Prostatic Stents

Microwave Therapy

Laser Prostatectomy

Summary of Minimally Invasive Treatments

Deciding on the Right Treatment for Each Patient


Source Information

From the Michigan Prostate Center, University of Michigan, 1500 E. Medical Center Dr., Ann Arbor, MI 48109, where reprint requests should be addressed to Dr. Oesterling.

References


Related Letters:

Treatment of Benign Prostatic Hyperplasia
Eisenberg L., Wasson J. H., Reda D. J., Bruskewitz R. C., Oesterling J. E.
Extract | Full Text  
N Engl J Med 1995; 332:1716-1717, Jun 22, 1995. Correspondence

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