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A 43-year-old woman presented in 1985 with Bowen's disease on the arm. During the subsequent eight years, she required treatment for a keratoacanthoma on the leg, a basal-cell carcinoma on the temple, a squamous-cell carcinoma on the chest, and multiple lesions of Bowen's disease on the buttocks and breasts, which had never been exposed to the sun (Figure 1).
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