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The development of sophisticated intensive care techniques for use in newborn infants has increased the survival of many critically ill and frequently very tiny neonates. Nevertheless, the incidence of developmental handicaps in those who survive has not changed over the past decade. Several reports indicate that the frequency of cerebral palsy is rising, and the average cost of hospital care for a low-birth-weight infant was recently reported to be almost $140,000 in 1989 dollars (J.A. Mauskopf, M.E. Backhouse, D. Jones, et al. Synthetic surfactant for rescue treatment of respiratory distress syndrome in premature infants weighing from 700 to 1350 grams:
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