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Previous Volume 332:238-248 January 26, 1995 Number 4 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Ischemic and hemorrhagic strokes are among the principal causes of death and disability in older people, although the incidence of such strokes is lower than in the past.^1,2 Control of blood pressure, decreased cigarette smoking, and possibly altered dietary habits are among the important but unconfirmed reasons proposed for this decline.^3,4,5 This review addresses the antithrombotic and surgical measures to prevent ischemic stroke that have been rigorously evaluated in randomized clinical trials.

Use of Anticoagulant Agents to Prevent Ischemic Stroke

Since the introduction of anticoagulant agents 50 years ago, their use has varied widely, which is to be expected for a treatment based on anecdotal evidence, case studies, . . . [Full Text of this Article]

Cardiac Disorders

Arteriosclerotic Lesions of the Cerebral Arteries

Prevention of Ischemic Stroke with Platelet Inhibitors

Clinical Trials of Platelet-Inhibiting Drugs

Meta-Analyses of Trials of Platelet-Inhibiting Drugs

Ticlopidine

Aspirin in Healthy Middle-Aged Subjects

Recommendations for Administering Platelet Inhibitors

Surgical Procedures to Prevent Stroke

Carotid Endarterectomy

            Symptomatic Carotid Artery Disease

            Ultrasonography as a Prelude to Carotid Endarterectomy

            Asymptomatic Carotid Artery Disease

            Asymptomatic Carotid-Artery Stenosis and Coronary-Artery Bypass Surgery

            Symptomatic Carotid-Artery Stenosis and Coronary-Artery Bypass Surgery

Extracranial-to-Intracranial Anastomosis

Percutaneous Transluminal Angioplasty for Cerebral-Artery Stenosis

Summary

Source Information

From the Departments of Clinical Neurological Sciences (H.J.M.B.) and Epidemiology and Biostatistics (M.E.), University of Western Ontario, and the John P. Robarts Research Institute (H.J.M.B., M.E., H.E.M.), both in London, Ont., Canada.

Address reprint requests to Dr. Barnett at the Robarts Research Institute, 100 Perth Dr., P.O. Box 5015, London, ON N6A 5K8, Canada.

References

Related Letters:

Prevention of Ischemic Stroke
Shear N. H., Appel C., Barnett H.J.M., Eliasziw M., Meldrum H. E.
Extract | Full Text  
N Engl J Med 1995; 333:460, Aug 17, 1995. Correspondence

Primary Prevention of Stroke
Martinez-Riera A., Santolaria-Fernandez F., Gonzalez-Reimers E., Perry I. J., Gilbert R.E., Jerums G., Cooper M.E., Bronner L. L., Kanter D. S., Manson J. E.
Extract | Full Text  
N Engl J Med 1996; 334:1138-1139, Apr 25, 1996. Correspondence

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