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Previous Volume 332:262-268 January 26, 1995 Number 4 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Financial conflicts of interest in a research setting can adversely affect patient care, teaching, and research. Discussions of these conflicts ordinarily focus on issues that arise when individual physicians and biomedical scientists conduct research in which they have a financial interest.^{1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18} Less attention has been paid to the conflicts of interest that arise when health care institutions have a financial stake in the research conducted in their laboratories and clinics.^19,20 This relative inattention persists despite the increased pressure on health care institutions to seek new sources of revenue to fund their activities and the government's encouragement of the commercialization of . . . [Full Text of this Article]

A Case of Institutional Conflict of Interest

Distinguishing between Individual and Institutional Conflicts of Interest

A Framework for Analyzing Institutional Conflicts of Interest

Conflict of Interest and Primary Missions

The Size of the Financial Interest

Professional Discretion in Patient Care and Biomedical Research

Potential Harm from Conflicts of Interest

            Patient Care

            Teaching

            Biomedical Research

Prima Facie Claim to Avoid Institutional Conflict of Interest

Safeguards against Harm from Institutional Conflicts of Interest

Disclosure

Internal Monitoring

External Monitoring

Application of the Framework to the Case of the Harvard-Affiliated Hospital

Additional Regulation of Institutional Conflicts of Interest

References

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