FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |   Search Term  Advanced Search

Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe

Previous Volume 332:262-268 January 26, 1995 Number 4 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text Purchase this article Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited PubMed Citation

Financial conflicts of interest in a research setting can adversely affect patient care, teaching, and research. Discussions of these conflicts ordinarily focus on issues that arise when individual physicians and biomedical scientists conduct research in which they have a financial interest.^{1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18} Less attention has been paid to the conflicts of interest that arise when health care institutions have a financial stake in the research conducted in their laboratories and clinics.^19,20 This relative inattention persists despite the increased pressure on health care institutions to seek new sources of revenue to fund their activities and the government's encouragement of the commercialization of . . . [Full Text of this Article]

A Case of Institutional Conflict of Interest

Distinguishing between Individual and Institutional Conflicts of Interest

A Framework for Analyzing Institutional Conflicts of Interest

Conflict of Interest and Primary Missions

The Size of the Financial Interest

Professional Discretion in Patient Care and Biomedical Research

Potential Harm from Conflicts of Interest

            Patient Care

            Teaching

            Biomedical Research

Prima Facie Claim to Avoid Institutional Conflict of Interest

Safeguards against Harm from Institutional Conflicts of Interest

Disclosure

Internal Monitoring

External Monitoring

Application of the Framework to the Case of the Harvard-Affiliated Hospital

Additional Regulation of Institutional Conflicts of Interest

References

This article has been cited by other articles:

• Ehringhaus, S. H., Weissman, J. S., Sears, J. L., Goold, S. D., Feibelmann, S., Campbell, E. G. (2008). Responses of Medical Schools to Institutional Conflicts of Interest. JAMA 299: 665-671 [Abstract] [Full Text]  
• Packer, S., Parke, D. W. II (2004). Ethical Concerns in Industry Support of Continuing Medical Education: The Con Side. Arch Ophthalmol 122: 773-776 [Full Text]  
• Kim, S Y H, Millard, R W, Nisbet, P, Cox, C, Caine, E D (2004). Potential research participants' views regarding researcher and institutional financial conflicts of interest. J. Med. Ethics 30: 73-79 [Abstract] [Full Text]  
• Johns, M. M. E., Barnes, M., Florencio, P. S. (2003). Restoring Balance to Industry-Academia Relationships in an Era of Institutional Financial Conflicts of Interest: Promoting Research While Maintaining Trust. JAMA 289: 741-746 [Abstract] [Full Text]  
• Bekelman, J. E., Li, Y., Gross, C. P. (2003). Scope and Impact of Financial Conflicts of Interest in Biomedical Research: A Systematic Review. JAMA 289: 454-465 [Abstract] [Full Text]  
• Emanuel, L., Cruess, R., Cruess, S., Hauser, J. (2002). Old values, new challenges: what is a professional to do?. Int J Qual Health Care 14: 349-351 [Full Text]  
• Barnes, M., Florencio, P. S. (2002). Financial Conflicts of Interest in Human Subjects Research: The Problem of Institutional Conflicts. J Law Med Ethics 30: 390-402  
• London, L. (2002). Ethical Oversight of Public Health Research: Can Rules and IRBs Make a Difference in Developing Countries?. AJPH 92: 1079-1084 [Abstract] [Full Text]  
• McCrary, S. V., Anderson, C. B., Jakovljevic, J., Khan, T., McCullough, L. B., Wray, N. P., Brody, B. A. (2000). A National Survey of Policies on Disclosure of Conflicts of Interest in Biomedical Research. NEJM 343: 1621-1626 [Abstract] [Full Text]  
• Emanuel, E. J., Goldman, L. (1998). Protecting Patient Welfare in Managed Care: Six Safeguards. Journal of Health Politics, Policy and Law 23: 635-659 [Abstract]