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Previous Volume 332:363-366 February 9, 1995 Number 6 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Whipple's disease is a multisystem bacterial disease usually characterized by malabsorption, diarrhea, and polyarthritis. Ocular manifestations of Whipple's disease include blurred vision or visual loss with one or more of the following findings: vitritis, uveitis, retinitis, retinal hemorrhage, choroiditis, papilledema, optic atrophy, and keratitis.¹ In general, these ocular manifestations occur in patients who also have gastrointestinal or central nervous system involvement.

We report a case of chronic, bilateral uveitis with unusual ophthalmologic features. The patient had no clinical evidence of gastrointestinal disease, and light microscopy of repeated duodenal-biopsy specimens was negative. A preliminary diagnosis of Whipple's disease was made on . . . [Full Text of this Article]

Case Report

Methods

Electron Microscopy

PCR Analysis

Results

Discussion

Source Information

From the Division of Infectious Diseases, Epidemiology Unit, and the Department of Internal Medicine (L.S.R.), the Department of Ophthalmology (W.R.F., S.T.F.), and the Department of Pathology (V.R.), University of California, San Diego; Johns Hopkins University, Baltimore (W.R.G.); and the Departments of Medicine and Microbiology and Immunology, Stanford University, Stanford, Calif., and the Veterans Affairs Medical Center, Palo Alto, Calif. (J.S., D.A.R.).

Address reprint requests to Dr. Rickman at the University of California, San Diego, Medical Center, 200 W. Arbor Dr., San Diego, CA 92103-8951.

References

This article has been cited by other articles:

• Fenollar, F., Puechal, X., Raoult, D. (2007). Whipple's Disease. NEJM 356: 55-66 [Full Text]  
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• Lange, U., Teichmann, J. (2003). Whipple arthritis: diagnosis by molecular analysis of synovial fluid--current status of diagnosis and therapy. Rheumatology (Oxford) 42: 473-480 [Abstract] [Full Text]  
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