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Previous Volume 332:461-463 February 16, 1995 Number 7 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Hodgkin's disease has been thought by some to be an infectious or inflammatory disease, but the Reed–Sternberg cells characteristic of the disorder are monoclonal and aneuploid and can form tumors in immunocompromised animals — characteristics of a malignant disorder.

In industrialized countries Hodgkin's disease has a bimodal age distribution; the first peak occurs between the ages of 15 and 35 years, and the second around the age of 50 years.¹ The distinctive epidemiologic characteristics of the two peaks suggest the existence of two diseases. Recent data demonstrate that the age-based incidence curves vary according to the histologic subtype: the nodular . . . [Full Text of this Article]

References

Related Letters:

Hodgkin's Disease and HIV Infection
Knopf K. B., Locker G. Y., Diehl V., Tesch H.
Extract | Full Text  
N Engl J Med 1995; 333:65-66, Jul 6, 1995. Correspondence

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